YB-1 Translational Control of Epithelial-Mesenchyme Transition

Research output: Contribution to journalShort surveypeer-review

Abstract

Transitions between epithelial and mesenchmal phenotypes play critical roles in normal development and cancer progression. In this issue of Cancer Cell, Evdokimova et al. demonstrate that YB-1 regulates epithelial-mesenchyme transition (EMT) by inducing cap-independent translation of mRNAs encoding EMT-promoting factors and suppressing cap-dependent translation of mRNAs encoding growth-promoting factors.

Original languageEnglish (US)
Pages (from-to)357-359
Number of pages3
JournalCancer Cell
Volume15
Issue number5
DOIs
StatePublished - May 5 2009
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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