YB-1 Translational Control of Epithelial-Mesenchyme Transition

Ghassan Mouneimne; Joan S. Brugge

doi:10.1016/j.ccr.2009.04.006

YB-1 Translational Control of Epithelial-Mesenchyme Transition

Ghassan Mouneimne, Joan S. Brugge

Research output: Contribution to journal › Short survey › peer-review

23 Scopus citations

Abstract

Transitions between epithelial and mesenchmal phenotypes play critical roles in normal development and cancer progression. In this issue of Cancer Cell, Evdokimova et al. demonstrate that YB-1 regulates epithelial-mesenchyme transition (EMT) by inducing cap-independent translation of mRNAs encoding EMT-promoting factors and suppressing cap-dependent translation of mRNAs encoding growth-promoting factors.

Original language	English (US)
Pages (from-to)	357-359
Number of pages	3
Journal	Cancer Cell
Volume	15
Issue number	5
DOIs	https://doi.org/10.1016/j.ccr.2009.04.006
State	Published - May 5 2009
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

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10.1016/j.ccr.2009.04.006

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title = "YB-1 Translational Control of Epithelial-Mesenchyme Transition",

abstract = "Transitions between epithelial and mesenchmal phenotypes play critical roles in normal development and cancer progression. In this issue of Cancer Cell, Evdokimova et al. demonstrate that YB-1 regulates epithelial-mesenchyme transition (EMT) by inducing cap-independent translation of mRNAs encoding EMT-promoting factors and suppressing cap-dependent translation of mRNAs encoding growth-promoting factors.",

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N2 - Transitions between epithelial and mesenchmal phenotypes play critical roles in normal development and cancer progression. In this issue of Cancer Cell, Evdokimova et al. demonstrate that YB-1 regulates epithelial-mesenchyme transition (EMT) by inducing cap-independent translation of mRNAs encoding EMT-promoting factors and suppressing cap-dependent translation of mRNAs encoding growth-promoting factors.

AB - Transitions between epithelial and mesenchmal phenotypes play critical roles in normal development and cancer progression. In this issue of Cancer Cell, Evdokimova et al. demonstrate that YB-1 regulates epithelial-mesenchyme transition (EMT) by inducing cap-independent translation of mRNAs encoding EMT-promoting factors and suppressing cap-dependent translation of mRNAs encoding growth-promoting factors.

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YB-1 Translational Control of Epithelial-Mesenchyme Transition

Abstract

ASJC Scopus subject areas

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