X-ray coherent scatter imaging for surgical margin detection: A Monte Carlo study

Manu N. Lakshmanan, Anuj J. Kapadia, Brian P. Harrawood, David Brady, Ehsan Samei

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

Instead of having the entire breast removed (a mastectomy), breast cancer patients often receive a breast con-serving surgery (BCS) for removal of only the breast tumor. If post-surgery analysis reveals ta missed margin around the tumor tissue excised through the BCS procedure, the physician must often call the patient back for another surgery, which is both difficult and risky for the patient. If this “margin detectionâ€could be performed during the BCS procedure itself, the surgical team could use the analysis to ensure that all tumor tissue was removed in a single surgery, thereby potentially reducing the number of call backs from breast cancer surgery. We describe here a potential technique to detect surgical tumor margins in breast cancer using x-ray coherent scatter imaging. In this study, we demonstrate the imaging ability of this technique using Monte Carlo simulations.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2014
Subtitle of host publicationPhysics of Medical Imaging
PublisherSPIE
ISBN (Print)9780819498267
DOIs
StatePublished - 2014
Externally publishedYes
EventMedical Imaging 2014: Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 17 2014Feb 20 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9033
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2014: Physics of Medical Imaging
Country/TerritoryUnited States
CitySan Diego, CA
Period2/17/142/20/14

Keywords

  • breast cancer
  • breast conserving surgery
  • intra-operative margin detection
  • x-ray coherent scatter imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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