Wikstromol, antitumor lignan from Wikstroemia foetida var. oahuensis gray and Wikstroemia uva‐ursi gray (thymelaeaceae)

Sterling J. Torrance; Joseph J. Hoffmann; Jack R. Cole

doi:10.1002/jps.2600680545

Wikstromol, antitumor lignan from Wikstroemia foetida var. oahuensis gray and Wikstroemia uva‐ursi gray (thymelaeaceae)

Sterling J. Torrance, Joseph J. Hoffmann, Jack R. Cole

Pharmacy Practice and Science

Research output: Contribution to journal › Comment/debate › peer-review

63 Scopus citations

Abstract

The ethanol extracts of Wikstroemia foetida var. oahuensis and Wikstroemia uva‐ursi showed antitumor activity against the P‐388 lymphocytic leukemia (3PS) test system. One PS‐active constituent of both plants was the lignan wikstromol. Several inactive compounds were identified as daphnoretin, pinoresinol, and syringaresinol.

Original language	English (US)
Pages (from-to)	664-665
Number of pages	2
Journal	Journal of pharmaceutical sciences
Volume	68
Issue number	5
DOIs	https://doi.org/10.1002/jps.2600680545
State	Published - May 1979

Keywords

Antineoplastic agents—wikstromol, isolated from plant material
Wikstromol—isolation from plant material, antineoplastic activity

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Pharmaceutical Science

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10.1002/jps.2600680545

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title = "Wikstromol, antitumor lignan from Wikstroemia foetida var. oahuensis gray and Wikstroemia uva‐ursi gray (thymelaeaceae)",

abstract = "The ethanol extracts of Wikstroemia foetida var. oahuensis and Wikstroemia uva‐ursi showed antitumor activity against the P‐388 lymphocytic leukemia (3PS) test system. One PS‐active constituent of both plants was the lignan wikstromol. Several inactive compounds were identified as daphnoretin, pinoresinol, and syringaresinol.",

keywords = "Antineoplastic agents—wikstromol, isolated from plant material, Wikstromol—isolation from plant material, antineoplastic activity",

author = "Torrance, {Sterling J.} and Hoffmann, {Joseph J.} and Cole, {Jack R.}",

note = "Funding Information: Supported in part by a grant from the CJniversity Research Institute, University of Texas at Austin.",

year = "1979",

month = may,

doi = "10.1002/jps.2600680545",

language = "English (US)",

volume = "68",

pages = "664--665",

journal = "Journal of pharmaceutical sciences",

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T1 - Wikstromol, antitumor lignan from Wikstroemia foetida var. oahuensis gray and Wikstroemia uva‐ursi gray (thymelaeaceae)

AU - Torrance, Sterling J.

AU - Hoffmann, Joseph J.

AU - Cole, Jack R.

N1 - Funding Information: Supported in part by a grant from the CJniversity Research Institute, University of Texas at Austin.

PY - 1979/5

Y1 - 1979/5

N2 - The ethanol extracts of Wikstroemia foetida var. oahuensis and Wikstroemia uva‐ursi showed antitumor activity against the P‐388 lymphocytic leukemia (3PS) test system. One PS‐active constituent of both plants was the lignan wikstromol. Several inactive compounds were identified as daphnoretin, pinoresinol, and syringaresinol.

AB - The ethanol extracts of Wikstroemia foetida var. oahuensis and Wikstroemia uva‐ursi showed antitumor activity against the P‐388 lymphocytic leukemia (3PS) test system. One PS‐active constituent of both plants was the lignan wikstromol. Several inactive compounds were identified as daphnoretin, pinoresinol, and syringaresinol.

KW - Antineoplastic agents—wikstromol, isolated from plant material

KW - Wikstromol—isolation from plant material, antineoplastic activity

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JO - Journal of pharmaceutical sciences

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ER -

Wikstromol, antitumor lignan from Wikstroemia foetida var. oahuensis gray and Wikstroemia uva‐ursi gray (thymelaeaceae)

Abstract

Keywords

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