When the fire won't go out: Pomegranate juice, sildenafil, CYP3A4

Thomas P. Pontinen; Randal O. Dull

doi:10.1007/978-1-4614-7495-1_192

When the fire won't go out: Pomegranate juice, sildenafil, CYP3A4

Thomas P. Pontinen
, Randal O. Dull

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This case discusses the pharmacokinetic interaction between pomegranate juice and sildenafil, resulting in priapism. Sildenafil is a cytochrome P450 3A4 substrate and pomegranate juice is a 3A4 inhibitor.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	859-861
Number of pages	3
ISBN (Electronic)	9781461474951
ISBN (Print)	9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_192
State	Published - Sep 15 2015
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4614-7495-1_192

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title = "When the fire won't go out: Pomegranate juice, sildenafil, CYP3A4",

abstract = "This case discusses the pharmacokinetic interaction between pomegranate juice and sildenafil, resulting in priapism. Sildenafil is a cytochrome P450 3A4 substrate and pomegranate juice is a 3A4 inhibitor.",

author = "Pontinen, \{Thomas P.\} and Dull, \{Randal O.\}",

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doi = "10.1007/978-1-4614-7495-1\_192",

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AU - Dull, Randal O.

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Y1 - 2015/9/15

N2 - This case discusses the pharmacokinetic interaction between pomegranate juice and sildenafil, resulting in priapism. Sildenafil is a cytochrome P450 3A4 substrate and pomegranate juice is a 3A4 inhibitor.

AB - This case discusses the pharmacokinetic interaction between pomegranate juice and sildenafil, resulting in priapism. Sildenafil is a cytochrome P450 3A4 substrate and pomegranate juice is a 3A4 inhibitor.

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U2 - 10.1007/978-1-4614-7495-1_192

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M3 - Chapter

AN - SCOPUS:84955368188

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EP - 861

BT - A Case Approach to Perioperative Drug-Drug Interactions

PB - Springer New York

ER -

When the fire won't go out: Pomegranate juice, sildenafil, CYP3A4

Abstract

ASJC Scopus subject areas

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