Vitamin D3 induced alteration of microvillar membrane lipid composition

David B.P. Goodman; Mark R. Haussler; Howard Rasmussen

doi:10.1016/0006-291X(72)90632-8

Vitamin D₃ induced alteration of microvillar membrane lipid composition

David B.P. Goodman, Mark R. Haussler, Howard Rasmussen

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

The lipid composition of microvillar membranes prepared from vitamin D₃-treated and vitamin D₃-deficient chick intestine has been investigated. Vitamin treatment results in an increase in the proportion of phospholipid in this target membrane as well as an alteration in the fatty acid composition of both membrane phospholipids and cholesterol esters. An increase in the weight percentage of several classes of phospholipid long chain polyunsaturated fatty acids results from vitamin treatment. The primary effect of vitamin treatment on cholesterol ester fatty acids appears to be in shorter chain species.

Original language	English (US)
Pages (from-to)	80-86
Number of pages	7
Journal	Biochemical and Biophysical Research Communications
Volume	46
Issue number	1
DOIs	https://doi.org/10.1016/0006-291X(72)90632-8
State	Published - Jan 14 1972
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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abstract = "The lipid composition of microvillar membranes prepared from vitamin D3-treated and vitamin D3-deficient chick intestine has been investigated. Vitamin treatment results in an increase in the proportion of phospholipid in this target membrane as well as an alteration in the fatty acid composition of both membrane phospholipids and cholesterol esters. An increase in the weight percentage of several classes of phospholipid long chain polyunsaturated fatty acids results from vitamin treatment. The primary effect of vitamin treatment on cholesterol ester fatty acids appears to be in shorter chain species.",

author = "Goodman, {David B.P.} and Haussler, {Mark R.} and Howard Rasmussen",

note = "Funding Information: ACKNOWLEDGEMENTS thank Mrs. Mattie Malone for expert technical was supported by USPHS Grant At4 09650. Dr.",

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AU - Goodman, David B.P.

AU - Haussler, Mark R.

AU - Rasmussen, Howard

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PY - 1972/1/14

Y1 - 1972/1/14

N2 - The lipid composition of microvillar membranes prepared from vitamin D3-treated and vitamin D3-deficient chick intestine has been investigated. Vitamin treatment results in an increase in the proportion of phospholipid in this target membrane as well as an alteration in the fatty acid composition of both membrane phospholipids and cholesterol esters. An increase in the weight percentage of several classes of phospholipid long chain polyunsaturated fatty acids results from vitamin treatment. The primary effect of vitamin treatment on cholesterol ester fatty acids appears to be in shorter chain species.

AB - The lipid composition of microvillar membranes prepared from vitamin D3-treated and vitamin D3-deficient chick intestine has been investigated. Vitamin treatment results in an increase in the proportion of phospholipid in this target membrane as well as an alteration in the fatty acid composition of both membrane phospholipids and cholesterol esters. An increase in the weight percentage of several classes of phospholipid long chain polyunsaturated fatty acids results from vitamin treatment. The primary effect of vitamin treatment on cholesterol ester fatty acids appears to be in shorter chain species.

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Vitamin D₃ induced alteration of microvillar membrane lipid composition

Abstract

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