Validation and Invalidation of SARS-CoV-2 Papain-like Protease Inhibitors

Keyphrases

• 6-mercaptopurine (6-MP) 10%
• 6-Thioguanine (6-TG) 10%
• Antiviral Drug Target 10%
• Binding Assay 30%
• Cell-based 10%
• COVID-19 100%
• Cryptotanshinone 10%
• Cysteine Protease 10%
• Denaturation 10%
• Dihydrotanshinone I 10%
• Enzymatic Inhibition 10%
• FlipGFP 20%
• FRET Assay 20%
• Gene Products 10%
• High-throughput Screening 10%
• Host Cell Proteins 10%
• Immune Regulation 10%
• Main Protease 10%
• Papain-like 100%
• Polyprotein 10%
• Protease 50%
• Protease Inhibitors 100%
• Proteasome Inhibition 10%
• Stimulator of Interferon Genes (STING) 10%
• Tanshinone I 10%
• Tanshinone IIA 10%
• Thermal Shift 20%
• Two-pronged Approach 10%
• Ubiquitin 10%
• Viral 20%
• YM155 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Antivirus Agent 10%
• Cryptotanshinone 10%
• Cysteine Proteinase 10%
• High-Throughput Screening 10%
• Interferon 10%
• Mercaptopurine 10%
• Papain 100%
• Polyprotein 10%
• Proteinase 70%
• Proteinase Inhibitor 100%
• SARS Coronavirus 100%
• Sepantronium Bromide 10%
• Tanshinone I 10%
• Tanshinone IIA 10%
• Tioguanine 10%
• Ubiquitin 10%