Uvaretin, a New Antitumor Agent from Uvaria acuminata (Annonaceae)

Jack R. Cole, Sterling J. Torrance, Richard M. Wiedhopf, Satish K. Arora, Robert B. Bates

Research output: Contribution to journalArticlepeer-review

53 Scopus citations


The chloroform extract of Uvaria acuminata Oliv. has shown inhibitory activity against the P-388 lymphocytic leukemia test system of the National Cancer Institute. The major constituent of this extract was identified as the new 3′-benzyldihydrochalcone uvaretin, 1-[2,4-dihydroxy-3-(2-hydroxybenzyl)-6-methoxyphenyl]-3-phenyl-lpropanone (C23H22O5)· The structure was proven by x-ray crystallography and other methods.

Original languageEnglish (US)
Pages (from-to)1852-1855
Number of pages4
JournalJournal of Organic Chemistry
Issue number10
StatePublished - May 1 1976

ASJC Scopus subject areas

  • Organic Chemistry


Dive into the research topics of 'Uvaretin, a New Antitumor Agent from Uvaria acuminata (Annonaceae)'. Together they form a unique fingerprint.

Cite this