Uterine rupture associated with recent antepartum cocaine abuse

Brian K. Iriye, Robert E. Bristow, Chaur Dong Hsu, Regina Bruni, Timothy R.B. Johnson

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Background: The diagnosis of uterine rupture is aided by the identification of risk factors, such as oxytocin administration. In several experiments, cocaine has been shown to stimulate uterine contractility. Complications from cocaine abuse during pregnancy have increased dramatically in the United States, and cocaine may increase the risk for uterine rupture. Cases: Two cases of uterine rupture were associated with recent cocaine abuse. Conclusion: These cases and recent experiments on the effect of cocaine on the pregnant uterus suggest that ante partum cocaine abuse may increase the risk of uterine rupture.

Original languageEnglish (US)
Pages (from-to)840-841
Number of pages2
JournalObstetrics and gynecology
Volume83
Issue number5
StatePublished - May 1994
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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