“Unexplained” Delayed Death From Fungal Meningitis After Meningioma Resection

R. John Hurlbert, Juan M. Bilbao, William S. Tucker

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Background: Progressive deterioration and ensuing death following a neurosurgical procedure often represents a diagnostic challenge to the team responsible for patient care. Many, but not all, causes are treatable if a diagnosis is made early. Methods: A 69-year-old woman who died 6 weeks post-operatively following a meningioma resection is reported. An initial routine post-operative course became complicated by progressive neurological deterioration 3–4 weeks later. Despite extensive investigation she died 6 weeks post-operatively without a diagnosis. Results: Autopsy demonstrated extensive Candida meningitis. A review of the literature demonstrates this to be a reported complication in high risk patients, difficult to diagnose, but treatable when identified. Conclusions: Fungal meningitis should be high in the differential diagnosis in the post-operative patient with delayed, unexplained neurological deterioration, especially when associated with negative CSF cultures.

Original languageEnglish (US)
Pages (from-to)239-243
Number of pages5
JournalCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Issue number3
StatePublished - Aug 1995

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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