TY - JOUR
T1 - Understanding the Impact of Residual Amblyopia on Functional Vision and Eye-related Quality of Life Using the PedEyeQ
AU - Hatt, Sarah R.
AU - Leske, David A.
AU - Castañeda, Yolanda S.
AU - Wernimont, Suzanne M.
AU - Liebermann, Laura
AU - Cheng-Patel, Christina S.
AU - Birch, Eileen E.
AU - Holmes, Jonathan M.
N1 - Funding Information:
Funding/Support: Financial assistance for this study came from National Institutes of Health Grants EY024333 (J.M.H. P.I. and E.E.B. Co-I) and EY022313 (E.E.B.), and Mayo Foundation, Rochester, Minnesota, USA. Financial Disclosures: None of the authors have any financial disclosures. All authors attest that they meet the current ICMJE criteria for authorship.
Publisher Copyright:
© 2020 Elsevier Inc.
PY - 2020/10
Y1 - 2020/10
N2 - Purpose: To evaluate the effect of residual amblyopia on functional vision and eye-related quality of life (ER-QOL) in children and their families using the Pediatric Eye Questionnaire (PedEyeQ). Design: Prospective cross-sectional study. Methods: Seventeen children with residual amblyopia (no current treatment except glasses), 48 visually normal controls without glasses, and 19 controls wearing glasses (aged 8-11 years) completed the Child 5-11 year PedEyeQ. One parent for each child completed the Proxy 5-11 PedEyeQ, Parent PedEyeQ. Rasch-calibrated domain scores were calculated for each questionnaire domain and compared between amblyopic children and controls. Results: PedEyeQ scores were significantly lower (worse) for children with residual amblyopia than for controls without glasses across all domains: Child PedEyeQ greatest mean difference 18 points worse on Functional vision domain (95% confidence interval [CI] −29 to −7; P < .001); Proxy PedEyeQ greatest mean difference 31 points worse on Functional vision domain (95% CI −39 to −24; P < .001); Parent PedEyeQ greatest mean difference 34 points worse on the Worry about child's eye condition domain (95% CI −46 to −22; P < .001). Compared with controls wearing glasses, PedEyeQ scores were lower for residual amblyopia on the Child Frustration/worry domain (P = .03), on 4 of 5 Proxy domains (P ≤ .05), and on 3 of 4 Parent domains (P ≤ .05). Conclusions: Residual amblyopia affects functional vision and ER-QOL in children. Parents of amblyopic children also experience lower quality of life. These data help broaden our understanding of the everyday-life impact of childhood residual amblyopia.
AB - Purpose: To evaluate the effect of residual amblyopia on functional vision and eye-related quality of life (ER-QOL) in children and their families using the Pediatric Eye Questionnaire (PedEyeQ). Design: Prospective cross-sectional study. Methods: Seventeen children with residual amblyopia (no current treatment except glasses), 48 visually normal controls without glasses, and 19 controls wearing glasses (aged 8-11 years) completed the Child 5-11 year PedEyeQ. One parent for each child completed the Proxy 5-11 PedEyeQ, Parent PedEyeQ. Rasch-calibrated domain scores were calculated for each questionnaire domain and compared between amblyopic children and controls. Results: PedEyeQ scores were significantly lower (worse) for children with residual amblyopia than for controls without glasses across all domains: Child PedEyeQ greatest mean difference 18 points worse on Functional vision domain (95% confidence interval [CI] −29 to −7; P < .001); Proxy PedEyeQ greatest mean difference 31 points worse on Functional vision domain (95% CI −39 to −24; P < .001); Parent PedEyeQ greatest mean difference 34 points worse on the Worry about child's eye condition domain (95% CI −46 to −22; P < .001). Compared with controls wearing glasses, PedEyeQ scores were lower for residual amblyopia on the Child Frustration/worry domain (P = .03), on 4 of 5 Proxy domains (P ≤ .05), and on 3 of 4 Parent domains (P ≤ .05). Conclusions: Residual amblyopia affects functional vision and ER-QOL in children. Parents of amblyopic children also experience lower quality of life. These data help broaden our understanding of the everyday-life impact of childhood residual amblyopia.
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U2 - 10.1016/j.ajo.2020.05.039
DO - 10.1016/j.ajo.2020.05.039
M3 - Article
C2 - 32511967
AN - SCOPUS:85089274749
SN - 0002-9394
VL - 218
SP - 173
EP - 181
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
ER -