Undercutting efforts of precision medicine: roadblocks to minority representation in breast cancer clinical trials

Geetanjali Saini; Keerthi Gogineni; Rick A. Kittles; Ritu Aneja

doi:10.1007/s10549-021-06264-x

Undercutting efforts of precision medicine: roadblocks to minority representation in breast cancer clinical trials

Geetanjali Saini, Keerthi Gogineni, Rick A. Kittles, Ritu Aneja

Surgery

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

Precision (or personalized) medicine holds great promise in the treatment of breast cancer. The success of personalized medicine is contingent upon inclusivity and representation for minority groups in clinical trials. In this article, we focus on the roadblocks for the African American demographic, including the barriers to access and enrollment in breast oncology trials, the prevailing classification of race and ethnicity, and the need to refine monolithic categorization by employing genetic ancestry mapping tools for a more accurate determination of race or ethnicity.

Original language	English (US)
Pages (from-to)	605-611
Number of pages	7
Journal	Breast Cancer Research and Treatment
Volume	187
Issue number	3
DOIs	https://doi.org/10.1007/s10549-021-06264-x
State	Published - Jun 2021

Keywords

African Americans
Ancestry informative markers
Oncology trials
Race/ethnicity classification

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1007/s10549-021-06264-x

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title = "Undercutting efforts of precision medicine: roadblocks to minority representation in breast cancer clinical trials",

abstract = "Precision (or personalized) medicine holds great promise in the treatment of breast cancer. The success of personalized medicine is contingent upon inclusivity and representation for minority groups in clinical trials. In this article, we focus on the roadblocks for the African American demographic, including the barriers to access and enrollment in breast oncology trials, the prevailing classification of race and ethnicity, and the need to refine monolithic categorization by employing genetic ancestry mapping tools for a more accurate determination of race or ethnicity.",

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author = "Geetanjali Saini and Keerthi Gogineni and Kittles, {Rick A.} and Ritu Aneja",

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AU - Saini, Geetanjali

AU - Gogineni, Keerthi

AU - Kittles, Rick A.

AU - Aneja, Ritu

PY - 2021/6

Y1 - 2021/6

N2 - Precision (or personalized) medicine holds great promise in the treatment of breast cancer. The success of personalized medicine is contingent upon inclusivity and representation for minority groups in clinical trials. In this article, we focus on the roadblocks for the African American demographic, including the barriers to access and enrollment in breast oncology trials, the prevailing classification of race and ethnicity, and the need to refine monolithic categorization by employing genetic ancestry mapping tools for a more accurate determination of race or ethnicity.

AB - Precision (or personalized) medicine holds great promise in the treatment of breast cancer. The success of personalized medicine is contingent upon inclusivity and representation for minority groups in clinical trials. In this article, we focus on the roadblocks for the African American demographic, including the barriers to access and enrollment in breast oncology trials, the prevailing classification of race and ethnicity, and the need to refine monolithic categorization by employing genetic ancestry mapping tools for a more accurate determination of race or ethnicity.

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KW - Ancestry informative markers

KW - Oncology trials

KW - Race/ethnicity classification

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JO - Breast Cancer Research and Treatment

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Undercutting efforts of precision medicine: roadblocks to minority representation in breast cancer clinical trials

Abstract

Keywords

ASJC Scopus subject areas

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