Ugi/Aldol sequence: Expeditious entry to several families of densely substituted nitrogen heterocycles

Zhigang Xu; Fabio De Moliner; Alexandra P. Cappelli; Christopher Hulme

doi:10.1002/anie.201202575

Ugi/Aldol sequence: Expeditious entry to several families of densely substituted nitrogen heterocycles

Zhigang Xu, Fabio De Moliner, Alexandra P. Cappelli, Christopher Hulme

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

Complexity from simplicity: Nitrogen-containing heterocycles have been assembled by means of unprecedented domino processes designed to take advantage of diversity assembly using strategically decorated Ugi products (see scheme). The aldol reaction is the second common denominator which enables sequences of up to five steps in one pot, thus producing unique molecular architectures in rapid fashion.

Original language	English (US)
Pages (from-to)	8037-8040
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	32
DOIs	https://doi.org/10.1002/anie.201202575
State	Published - Aug 6 2012

Keywords

aldol reaction
molecular diversity
multicomponent reactions
nitrogen heterocycles
synthetic methods

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.201202575

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abstract = "Complexity from simplicity: Nitrogen-containing heterocycles have been assembled by means of unprecedented domino processes designed to take advantage of diversity assembly using strategically decorated Ugi products (see scheme). The aldol reaction is the second common denominator which enables sequences of up to five steps in one pot, thus producing unique molecular architectures in rapid fashion.",

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AU - Cappelli, Alexandra P.

AU - Hulme, Christopher

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KW - synthetic methods

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Ugi/Aldol sequence: Expeditious entry to several families of densely substituted nitrogen heterocycles

Abstract

Keywords

ASJC Scopus subject areas

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