Ubiquitin-dependent control of development in Saccharomyces cerevisiae

Jeffrey D. Laney, Mark Hochstrasser

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


In response to external environmental stimuli and intrinsic developmental cues, yeast cells reset their gene expression programs and change phenotype. These switches in cellular state require the dismantling of an initial regulatory program, in addition to the induction of different sets of genes to specify the new cell phenotype. Recent experiments examining the role of protein degradation in these transitions have highlighted the importance of inactivating previously utilized regulators and have led to advances in our understanding of how cells change from one phenotypic state to another.

Original languageEnglish (US)
Pages (from-to)647-654
Number of pages8
JournalCurrent Opinion in Microbiology
Issue number6
StatePublished - Dec 2004
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases


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