Types of natural selection and tests of selection

David Enard

doi:10.1007/978-3-030-61646-5_4

Types of natural selection and tests of selection

David Enard

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

Natural selection leaves distinct signals at loci in the genome that have experienced deleterious or advantageous mutations during their evolution. This chapter provides an overview of the main signatures left by natural selection both at the level of genetic variation within populations and at the level of differences between species. The chapter also details a number of classic summary statistics that exploit these signals to detect and quantify natural selection and the rationale behind these statistics. As such, it offers a basic introduction.

Original language	English (US)
Title of host publication	Human Population Genomics
Subtitle of host publication	Introduction to Essential Concepts and Applications
Publisher	Springer International Publishing
Pages	69-86
Number of pages	18
ISBN (Electronic)	9783030616465
ISBN (Print)	9783030616441
DOIs	https://doi.org/10.1007/978-3-030-61646-5_4
State	Published - Apr 14 2021
Externally published	Yes

Keywords

Background selection
Balancing selection
Haplotype
Hitchhiking
Selective sweep
Site frequency spectrum

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Mathematics
General Medicine

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10.1007/978-3-030-61646-5_4

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KW - Hitchhiking

KW - Selective sweep

KW - Site frequency spectrum

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Types of natural selection and tests of selection

Abstract

Keywords

ASJC Scopus subject areas

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