Two strains of baboon endogenous virus demonstrate a high degree of genetic conservation

Edward P. Gelmann; Steven F. Josephs; Flossie Wong-Staal

doi:10.1016/0378-1119(83)90157-9

Two strains of baboon endogenous virus demonstrate a high degree of genetic conservation

Edward P. Gelmann, Steven F. Josephs, Flossie Wong-Staal

Research output: Contribution to journal › Article › peer-review

Abstract

Molecular clones of the baboon endogenous viruses 455K, from Papio anubis, and M₇, from Papio cynocephalus, have been constructed from unintegrated viral DNA. Although two specific restriction sites do distinguish the two, detailed restriction maps are nearly identical and heteroduplex molecules show complete homology. The latter observations indicate that this endogenous retrovirus genome has been strongly conserved among different species of baboon.

Original language	English (US)
Pages (from-to)	161-164
Number of pages	4
Journal	Gene
Volume	21
Issue number	1-2
DOIs	https://doi.org/10.1016/0378-1119(83)90157-9
State	Published - 1983
Externally published	Yes

Keywords

Papio anubis
Recombinant DNA
heteroduplexes
primate retrovirus
λ Charon vectors cloning

ASJC Scopus subject areas

Genetics

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10.1016/0378-1119(83)90157-9

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abstract = "Molecular clones of the baboon endogenous viruses 455K, from Papio anubis, and M7, from Papio cynocephalus, have been constructed from unintegrated viral DNA. Although two specific restriction sites do distinguish the two, detailed restriction maps are nearly identical and heteroduplex molecules show complete homology. The latter observations indicate that this endogenous retrovirus genome has been strongly conserved among different species of baboon.",

keywords = "Papio anubis, Recombinant DNA, heteroduplexes, primate retrovirus, λ Charon vectors cloning",

author = "Gelmann, {Edward P.} and Josephs, {Steven F.} and Flossie Wong-Staal",

year = "1983",

doi = "10.1016/0378-1119(83)90157-9",

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AU - Gelmann, Edward P.

AU - Josephs, Steven F.

AU - Wong-Staal, Flossie

PY - 1983

Y1 - 1983

N2 - Molecular clones of the baboon endogenous viruses 455K, from Papio anubis, and M7, from Papio cynocephalus, have been constructed from unintegrated viral DNA. Although two specific restriction sites do distinguish the two, detailed restriction maps are nearly identical and heteroduplex molecules show complete homology. The latter observations indicate that this endogenous retrovirus genome has been strongly conserved among different species of baboon.

AB - Molecular clones of the baboon endogenous viruses 455K, from Papio anubis, and M7, from Papio cynocephalus, have been constructed from unintegrated viral DNA. Although two specific restriction sites do distinguish the two, detailed restriction maps are nearly identical and heteroduplex molecules show complete homology. The latter observations indicate that this endogenous retrovirus genome has been strongly conserved among different species of baboon.

KW - Papio anubis

KW - Recombinant DNA

KW - heteroduplexes

KW - primate retrovirus

KW - λ Charon vectors cloning

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U2 - 10.1016/0378-1119(83)90157-9

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JO - Gene

JF - Gene

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ER -

Two strains of baboon endogenous virus demonstrate a high degree of genetic conservation

Abstract

Keywords

ASJC Scopus subject areas

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