Abstract
The novel solution-phase synthesis of an array of biologically relevant quinoxalinones in a simple two-step procedure is revealed. Transformations are carried out in excellent yield by condensation of mono-Boc protected ortho-phenylene di-amine, glyoxylic acids and supporting Ugi reagents. Subsequent acid treatment and evaporation affords quinoxalinones in good to excellent yields.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1637-1639 |
| Number of pages | 3 |
| Journal | Tetrahedron Letters |
| Volume | 43 |
| Issue number | 9 |
| DOIs | |
| State | Published - Feb 25 2002 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
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