Tumor‐inhibitory agent from Zaluzania robinsonii (compositae)

S. D. Jolad; R. M. Wiedhopf; J. R. Cole

doi:10.1002/jps.2600630840

Tumor‐inhibitory agent from Zaluzania robinsonii (compositae)

S. D. Jolad, R. M. Wiedhopf, J. R. Cole

Pharmacy Practice and Science

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

The chloroform extract of Zaluzania robinsonii Sharp has shown activity against the P‐388 lymphocytic leukemia test system. The constituent responsible for this activity was a guaianolide, identified as zaluzanin C (₁₅H₁₈O₃). The identity was proven by melting point, mixed melting point, elemental analysis, IR, PMR, mass spectroscopy, and preparation of derivatives.

Original language	English (US)
Pages (from-to)	1321-1322
Number of pages	2
Journal	Journal of pharmaceutical sciences
Volume	63
Issue number	8
DOIs	https://doi.org/10.1002/jps.2600630840
State	Published - Aug 1974

Keywords

Antitumor agents, potential—isolation, identification, and screening of zaluzanin C from Z. robinsonii
Zaluzania robinsonii (Compositae)—isolation and identification of zaluzanin C as tumor‐inhibiting agent
Zaluzanin C‐isolation and identification from Z. robinsonii, tested for tumor‐inhibitory activity

ASJC Scopus subject areas

Pharmaceutical Science

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10.1002/jps.2600630840

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title = "Tumor‐inhibitory agent from Zaluzania robinsonii (compositae)",

abstract = "The chloroform extract of Zaluzania robinsonii Sharp has shown activity against the P‐388 lymphocytic leukemia test system. The constituent responsible for this activity was a guaianolide, identified as zaluzanin C (15H18O3). The identity was proven by melting point, mixed melting point, elemental analysis, IR, PMR, mass spectroscopy, and preparation of derivatives.",

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author = "Jolad, {S. D.} and Wiedhopf, {R. M.} and Cole, {J. R.}",

year = "1974",

month = aug,

doi = "10.1002/jps.2600630840",

language = "English (US)",

volume = "63",

pages = "1321--1322",

journal = "Journal of pharmaceutical sciences",

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T1 - Tumor‐inhibitory agent from Zaluzania robinsonii (compositae)

AU - Jolad, S. D.

AU - Wiedhopf, R. M.

AU - Cole, J. R.

PY - 1974/8

Y1 - 1974/8

N2 - The chloroform extract of Zaluzania robinsonii Sharp has shown activity against the P‐388 lymphocytic leukemia test system. The constituent responsible for this activity was a guaianolide, identified as zaluzanin C (15H18O3). The identity was proven by melting point, mixed melting point, elemental analysis, IR, PMR, mass spectroscopy, and preparation of derivatives.

AB - The chloroform extract of Zaluzania robinsonii Sharp has shown activity against the P‐388 lymphocytic leukemia test system. The constituent responsible for this activity was a guaianolide, identified as zaluzanin C (15H18O3). The identity was proven by melting point, mixed melting point, elemental analysis, IR, PMR, mass spectroscopy, and preparation of derivatives.

KW - Antitumor agents, potential—isolation, identification, and screening of zaluzanin C from Z. robinsonii

KW - Zaluzania robinsonii (Compositae)—isolation and identification of zaluzanin C as tumor‐inhibiting agent

KW - Zaluzanin C‐isolation and identification from Z. robinsonii, tested for tumor‐inhibitory activity

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Tumor‐inhibitory agent from Zaluzania robinsonii (compositae)

Abstract

Keywords

ASJC Scopus subject areas

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