Tumor‐inhibitory agent from Montezuma speciosissima (malvaceae)

S. D. Jolad; R. M. Wiedhopf; J. R. Cole

doi:10.1002/jps.2600641134

Tumor‐inhibitory agent from Montezuma speciosissima (malvaceae)

S. D. Jolad, R. M. Wiedhopf, J. R. Cole

Pharmacy Practice and Science

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The petroleum ether extract of Montezuma speciosissima Sesse and Moc. demonstrated tumor‐inhibiting properties in the P‐388 lymphocytic leukemia test system (3PS). The constituent responsible for this activity was shown to be a symmetrically substituted 2, 2′‐dinaphthol, identified as gossypol (C₃₀H₃₀O₈).

Original language	English (US)
Pages (from-to)	1889-1890
Number of pages	2
Journal	Journal of pharmaceutical sciences
Volume	64
Issue number	11
DOIs	https://doi.org/10.1002/jps.2600641134
State	Published - Nov 1975

Keywords

Gossypol—isolated from Montezuma speciosissima, PMR, UV, IR, and mass spectra, tumor inhibitory activity
Montezuma speciosissima—extract, PMR, UV, IR, and mass spectra, gossypol isolated
Tumor inhibition—gossypol, isolated from Montezuma speciosissima, PMR, UV, IR, and mass spectra

ASJC Scopus subject areas

Pharmaceutical Science

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10.1002/jps.2600641134

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title = "Tumor‐inhibitory agent from Montezuma speciosissima (malvaceae)",

abstract = "The petroleum ether extract of Montezuma speciosissima Sesse and Moc. demonstrated tumor‐inhibiting properties in the P‐388 lymphocytic leukemia test system (3PS). The constituent responsible for this activity was shown to be a symmetrically substituted 2, 2′‐dinaphthol, identified as gossypol (C30H30O8).",

keywords = "Gossypol—isolated from Montezuma speciosissima, PMR, UV, IR, and mass spectra, tumor inhibitory activity, Montezuma speciosissima—extract, PMR, UV, IR, and mass spectra, gossypol isolated, Tumor inhibition—gossypol, isolated from Montezuma speciosissima, PMR, UV, IR, and mass spectra",

author = "Jolad, {S. D.} and Wiedhopf, {R. M.} and Cole, {J. R.}",

year = "1975",

month = nov,

doi = "10.1002/jps.2600641134",

language = "English (US)",

volume = "64",

pages = "1889--1890",

journal = "Journal of pharmaceutical sciences",

issn = "0022-3549",

publisher = "Elsevier B.V.",

number = "11",

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T1 - Tumor‐inhibitory agent from Montezuma speciosissima (malvaceae)

AU - Jolad, S. D.

AU - Wiedhopf, R. M.

AU - Cole, J. R.

PY - 1975/11

Y1 - 1975/11

N2 - The petroleum ether extract of Montezuma speciosissima Sesse and Moc. demonstrated tumor‐inhibiting properties in the P‐388 lymphocytic leukemia test system (3PS). The constituent responsible for this activity was shown to be a symmetrically substituted 2, 2′‐dinaphthol, identified as gossypol (C30H30O8).

AB - The petroleum ether extract of Montezuma speciosissima Sesse and Moc. demonstrated tumor‐inhibiting properties in the P‐388 lymphocytic leukemia test system (3PS). The constituent responsible for this activity was shown to be a symmetrically substituted 2, 2′‐dinaphthol, identified as gossypol (C30H30O8).

KW - Gossypol—isolated from Montezuma speciosissima, PMR, UV, IR, and mass spectra, tumor inhibitory activity

KW - Montezuma speciosissima—extract, PMR, UV, IR, and mass spectra, gossypol isolated

KW - Tumor inhibition—gossypol, isolated from Montezuma speciosissima, PMR, UV, IR, and mass spectra

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DO - 10.1002/jps.2600641134

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AN - SCOPUS:0016801218

SN - 0022-3549

VL - 64

SP - 1889

EP - 1890

JO - Journal of pharmaceutical sciences

JF - Journal of pharmaceutical sciences

IS - 11

ER -

Tumor‐inhibitory agent from Montezuma speciosissima (malvaceae)

Abstract

Keywords

ASJC Scopus subject areas

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