tsRNAs: The Swiss Army Knife for Translational Regulation

Junchao Shi, Yunfang Zhang, Tong Zhou, Qi Chen

Research output: Contribution to journalShort surveypeer-review

56 Scopus citations


tRNA-derived small RNAs (tsRNAs, or tRFs) are a new category of regulatory noncoding RNAs with versatile functions. Recent emerging studies have begun to unveil distinct features of tsRNAs based on their sequence, RNA modifications, and structures that differentially impact their functions towards regulating multiple aspects of translational control and ribosome biogenesis.

Original languageEnglish (US)
Pages (from-to)185-189
Number of pages5
JournalTrends in Biochemical Sciences
Issue number3
StatePublished - Mar 2019


  • RNA modification
  • RNA structure
  • ribosome
  • tRNA-derived small RNA
  • translational regulation

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology


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