Treatment of nonmetastatic gestational trophoblastic disease with sequential intramuscular and oral methotrexate

James F. Barter; Kenneth D. Hatch; James W. Orr; Edward C. Partridge; J. Maxwell Austin; Hugh M. Shingleton; Seng Jaw Soong

doi:10.1016/0090-8258(89)90608-2

Treatment of nonmetastatic gestational trophoblastic disease with sequential intramuscular and oral methotrexate

James F. Barter
, Kenneth D. Hatch
, James W. Orr
, Edward C. Partridge
, J. Maxwell Austin
, Hugh M. Shingleton
, Seng Jaw Soong

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Thirty-seven patients with nonmetastatic gestational trophoblastic disease (NMGTD) were treated with one or more cycles of oral methotrexate following intramuscular methotrexate as part of induction chemotherapy. Remission was achieved in 31 patients (83.8%). All failures were readily cured with alternate regimens. Prospective studies using this safe, easily administered modality are needed to verify its apparent efficacy.

Original language	English (US)
Pages (from-to)	82-84
Number of pages	3
Journal	Gynecologic oncology
Volume	33
Issue number	1
DOIs	https://doi.org/10.1016/0090-8258(89)90608-2
State	Published - Apr 1989

ASJC Scopus subject areas

Oncology
Obstetrics and Gynecology

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title = "Treatment of nonmetastatic gestational trophoblastic disease with sequential intramuscular and oral methotrexate",

abstract = "Thirty-seven patients with nonmetastatic gestational trophoblastic disease (NMGTD) were treated with one or more cycles of oral methotrexate following intramuscular methotrexate as part of induction chemotherapy. Remission was achieved in 31 patients (83.8\%). All failures were readily cured with alternate regimens. Prospective studies using this safe, easily administered modality are needed to verify its apparent efficacy.",

author = "Barter, \{James F.\} and Hatch, \{Kenneth D.\} and Orr, \{James W.\} and Partridge, \{Edward C.\} and Austin, \{J. Maxwell\} and Shingleton, \{Hugh M.\} and Soong, \{Seng Jaw\}",

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AU - Barter, James F.

AU - Hatch, Kenneth D.

AU - Orr, James W.

AU - Partridge, Edward C.

AU - Austin, J. Maxwell

AU - Shingleton, Hugh M.

AU - Soong, Seng Jaw

PY - 1989/4

Y1 - 1989/4

N2 - Thirty-seven patients with nonmetastatic gestational trophoblastic disease (NMGTD) were treated with one or more cycles of oral methotrexate following intramuscular methotrexate as part of induction chemotherapy. Remission was achieved in 31 patients (83.8%). All failures were readily cured with alternate regimens. Prospective studies using this safe, easily administered modality are needed to verify its apparent efficacy.

AB - Thirty-seven patients with nonmetastatic gestational trophoblastic disease (NMGTD) were treated with one or more cycles of oral methotrexate following intramuscular methotrexate as part of induction chemotherapy. Remission was achieved in 31 patients (83.8%). All failures were readily cured with alternate regimens. Prospective studies using this safe, easily administered modality are needed to verify its apparent efficacy.

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AN - SCOPUS:0024502233

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Treatment of nonmetastatic gestational trophoblastic disease with sequential intramuscular and oral methotrexate

Abstract

ASJC Scopus subject areas

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