Treatment of nonmetastatic gestational trophoblastic disease with oral methotrexate

James F. Barter; Seng Jaw Soong; Kenneth D. Hatch; James W. Orr; Edward C. Partridge; J. Maxwell Austin; Hugh M. Shingleton

doi:10.1016/S0002-9378(87)80285-5

Treatment of nonmetastatic gestational trophoblastic disease with oral methotrexate

James F. Barter, Seng Jaw Soong, Kenneth D. Hatch, James W. Orr, Edward C. Partridge, J. Maxwell Austin, Hugh M. Shingleton

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Fifteen patients with nonmetastatic gestational trophoblastic disease were treated solely with methotrexate given orally rather than intramuscularly. Remission, defined as a ti-human chorionic gonadotropin titer of <5 mlU/ml for 3 consecutive weeks, was attained in 13 (87%) of the 15 patients. Level of toxicity was acceptable. Patient comfort, convenience, and less time off work and in the physician's office are significant advantages to this efficacious, well-tolerated method of therapy.

Original language	English (US)
Pages (from-to)	1166-1168
Number of pages	3
Journal	American journal of obstetrics and gynecology
Volume	157
Issue number	5
DOIs	https://doi.org/10.1016/S0002-9378(87)80285-5
State	Published - 1987

Keywords

Gestational trophoblastic disease
oral methotrexate

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1016/S0002-9378(87)80285-5

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title = "Treatment of nonmetastatic gestational trophoblastic disease with oral methotrexate",

abstract = "Fifteen patients with nonmetastatic gestational trophoblastic disease were treated solely with methotrexate given orally rather than intramuscularly. Remission, defined as a ti-human chorionic gonadotropin titer of <5 mlU/ml for 3 consecutive weeks, was attained in 13 (87%) of the 15 patients. Level of toxicity was acceptable. Patient comfort, convenience, and less time off work and in the physician's office are significant advantages to this efficacious, well-tolerated method of therapy.",

keywords = "Gestational trophoblastic disease, oral methotrexate",

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doi = "10.1016/S0002-9378(87)80285-5",

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AU - Barter, James F.

AU - Soong, Seng Jaw

AU - Hatch, Kenneth D.

AU - Orr, James W.

AU - Partridge, Edward C.

AU - Austin, J. Maxwell

AU - Shingleton, Hugh M.

PY - 1987

Y1 - 1987

N2 - Fifteen patients with nonmetastatic gestational trophoblastic disease were treated solely with methotrexate given orally rather than intramuscularly. Remission, defined as a ti-human chorionic gonadotropin titer of <5 mlU/ml for 3 consecutive weeks, was attained in 13 (87%) of the 15 patients. Level of toxicity was acceptable. Patient comfort, convenience, and less time off work and in the physician's office are significant advantages to this efficacious, well-tolerated method of therapy.

AB - Fifteen patients with nonmetastatic gestational trophoblastic disease were treated solely with methotrexate given orally rather than intramuscularly. Remission, defined as a ti-human chorionic gonadotropin titer of <5 mlU/ml for 3 consecutive weeks, was attained in 13 (87%) of the 15 patients. Level of toxicity was acceptable. Patient comfort, convenience, and less time off work and in the physician's office are significant advantages to this efficacious, well-tolerated method of therapy.

KW - Gestational trophoblastic disease

KW - oral methotrexate

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ER -

Treatment of nonmetastatic gestational trophoblastic disease with oral methotrexate

Abstract

Keywords

ASJC Scopus subject areas

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