Treatment of hairy cell leukemia with alpha interferons

Jorge R. Quesada, Jordan U. Gutterman, Evan M. Hersh

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

A review of clinical research with alpha interferons in the treatment of hairy cell leukemia is presented. The results of several studies have shown that alpha interferons effectively reduce leukemic infiltrates in the bone marrow and other organswith attendant resolution of cytopenias. Alpha interferons have shown efficacy in the treatment of patients in all clinical stages of the diseaseincluding those previously untreatedand may become the treatment choice for hairy cell leukemia. Hairy cell leukemia will also provide a useful human clinical model in which some of the fundamental mechanisms of interferon activity can be studied.

Original languageEnglish (US)
Pages (from-to)1678-1680
Number of pages3
JournalCancer
Volume57
Issue number8 S
DOIs
StatePublished - Apr 15 1986
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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