Transcription and Epigenetic Regulation

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter covers the broad field of transcription and epigenetic regulatory mechanisms to equip the gastrointestinal physiologist with the tools to understand gene expression. This chapter reviews the composition of the nucleic acids and the methods used to study their structure and function. The effect of noncoding RNA species such as microRNA and long noncoding RNAs is discussed. In addition, the impact of histone and DNA modification on gene expression collectively known as epigenetic influences are discussed in the context of how the gut microenvironment.

Original languageEnglish (US)
Title of host publicationPhysiology of the Gastrointestinal Tract
Subtitle of host publicationSixth Edition
PublisherElsevier Inc.
Number of pages28
ISBN (Electronic)9780128124260
ISBN (Print)9780128099544
StatePublished - Mar 28 2018
Externally publishedYes


  • Chromatin
  • Histone
  • Long-noncoding RNA
  • MiRNA
  • Nuclear export
  • Polymerase 2

ASJC Scopus subject areas

  • Medicine(all)


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