Trans-synaptic degeneration of the optic radiation from optic nerve atrophy

Shingo Kihira; Anthony C. Arnold; Puneet S. Pawha; Pablo Villablanca; Kambiz Nael

doi:10.1016/j.radcr.2021.01.017

Trans-synaptic degeneration of the optic radiation from optic nerve atrophy

Shingo Kihira
, Anthony C. Arnold
, Puneet S. Pawha
, Pablo Villablanca
, Kambiz Nael

Medical Imaging

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Fourty-seven-year-old woman with 5-year history of progressive decreased left eye vision. Optical coherence tomography showed optic nerve atrophy (left > right) and brain MRI revealed T2 hyperintense signal along the course of left optic radiations. We present a case of a trans-synaptic degeneration of the optic radiation in a patient with confirmed optic atrophy. Trans-synaptic degeneration of the optic radiation without associated infarct or inflammatory disease has not been reported before in patients with optic atrophy.

Original language	English (US)
Pages (from-to)	855-857
Number of pages	3
Journal	Radiology Case Reports
Volume	16
Issue number	4
DOIs	https://doi.org/10.1016/j.radcr.2021.01.017
State	Published - Apr 2021

Keywords

Optic nerve atrophy
Optic radiation
Trans-synaptic degeneration

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.radcr.2021.01.017

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title = "Trans-synaptic degeneration of the optic radiation from optic nerve atrophy",

abstract = "Fourty-seven-year-old woman with 5-year history of progressive decreased left eye vision. Optical coherence tomography showed optic nerve atrophy (left > right) and brain MRI revealed T2 hyperintense signal along the course of left optic radiations. We present a case of a trans-synaptic degeneration of the optic radiation in a patient with confirmed optic atrophy. Trans-synaptic degeneration of the optic radiation without associated infarct or inflammatory disease has not been reported before in patients with optic atrophy.",

keywords = "Optic nerve atrophy, Optic radiation, Trans-synaptic degeneration",

author = "Shingo Kihira and Arnold, \{Anthony C.\} and Pawha, \{Puneet S.\} and Pablo Villablanca and Kambiz Nael",

note = "Publisher Copyright: {\textcopyright} 2021",

year = "2021",

month = apr,

doi = "10.1016/j.radcr.2021.01.017",

language = "English (US)",

volume = "16",

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TY - JOUR

T1 - Trans-synaptic degeneration of the optic radiation from optic nerve atrophy

AU - Kihira, Shingo

AU - Arnold, Anthony C.

AU - Pawha, Puneet S.

AU - Villablanca, Pablo

AU - Nael, Kambiz

PY - 2021/4

Y1 - 2021/4

N2 - Fourty-seven-year-old woman with 5-year history of progressive decreased left eye vision. Optical coherence tomography showed optic nerve atrophy (left > right) and brain MRI revealed T2 hyperintense signal along the course of left optic radiations. We present a case of a trans-synaptic degeneration of the optic radiation in a patient with confirmed optic atrophy. Trans-synaptic degeneration of the optic radiation without associated infarct or inflammatory disease has not been reported before in patients with optic atrophy.

AB - Fourty-seven-year-old woman with 5-year history of progressive decreased left eye vision. Optical coherence tomography showed optic nerve atrophy (left > right) and brain MRI revealed T2 hyperintense signal along the course of left optic radiations. We present a case of a trans-synaptic degeneration of the optic radiation in a patient with confirmed optic atrophy. Trans-synaptic degeneration of the optic radiation without associated infarct or inflammatory disease has not been reported before in patients with optic atrophy.

KW - Optic nerve atrophy

KW - Optic radiation

KW - Trans-synaptic degeneration

UR - https://www.scopus.com/pages/publications/85100027925

UR - https://www.scopus.com/pages/publications/85100027925#tab=citedBy

U2 - 10.1016/j.radcr.2021.01.017

DO - 10.1016/j.radcr.2021.01.017

M3 - Article

AN - SCOPUS:85100027925

SN - 1930-0433

VL - 16

SP - 855

EP - 857

JO - Radiology Case Reports

JF - Radiology Case Reports

IS - 4

ER -

Trans-synaptic degeneration of the optic radiation from optic nerve atrophy

Abstract

Keywords

ASJC Scopus subject areas

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