Trans-synaptic degeneration of the optic radiation from optic nerve atrophy

Shingo Kihira, Anthony C. Arnold, Puneet S. Pawha, Pablo Villablanca, Kambiz Nael

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Fourty-seven-year-old woman with 5-year history of progressive decreased left eye vision. Optical coherence tomography showed optic nerve atrophy (left > right) and brain MRI revealed T2 hyperintense signal along the course of left optic radiations. We present a case of a trans-synaptic degeneration of the optic radiation in a patient with confirmed optic atrophy. Trans-synaptic degeneration of the optic radiation without associated infarct or inflammatory disease has not been reported before in patients with optic atrophy.

Original languageEnglish (US)
Pages (from-to)855-857
Number of pages3
JournalRadiology Case Reports
Issue number4
StatePublished - Apr 2021


  • Optic nerve atrophy
  • Optic radiation
  • Trans-synaptic degeneration

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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