Abstract
Polyene synthesis: An efficient approach to the total synthesis of polyene natural product dihydroxrulin (1) is described. A novel, mild, direct organocatalytic IBX-mediated dehydrogenation process of simple alcohols to enals has been developed, which serves as a key step in the synthesis (see scheme).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2230-2234 |
| Number of pages | 5 |
| Journal | Chemistry - A European Journal |
| Volume | 18 |
| Issue number | 8 |
| DOIs | |
| State | Published - Feb 20 2012 |
| Externally published | Yes |
Keywords
- dehydrogenation
- dihydroxerulin
- enals
- organocatalysis
- oxidative enamine catalysis
- polyenes
ASJC Scopus subject areas
- General Chemistry
- Catalysis
- Organic Chemistry