Total synthesis of polyene natural product dihydroxerulin by mild organocatalyzed dehydrogenation of alcohols

Hexin Xie; Shilei Zhang; Hao Li; Xinshuai Zhang; Sihan Zhao; Zian Xu; Xixi Song; Xinhong Yu; Wei Wang

doi:10.1002/chem.201103325

Total synthesis of polyene natural product dihydroxerulin by mild organocatalyzed dehydrogenation of alcohols

Hexin Xie, Shilei Zhang, Hao Li, Xinshuai Zhang, Sihan Zhao, Zian Xu, Xixi Song, Xinhong Yu, Wei Wang

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Polyene synthesis: An efficient approach to the total synthesis of polyene natural product dihydroxrulin (1) is described. A novel, mild, direct organocatalytic IBX-mediated dehydrogenation process of simple alcohols to enals has been developed, which serves as a key step in the synthesis (see scheme).

Original language	English (US)
Pages (from-to)	2230-2234
Number of pages	5
Journal	Chemistry - A European Journal
Volume	18
Issue number	8
DOIs	https://doi.org/10.1002/chem.201103325
State	Published - Feb 20 2012
Externally published	Yes

Keywords

dehydrogenation
dihydroxerulin
enals
organocatalysis
oxidative enamine catalysis
polyenes

ASJC Scopus subject areas

General Chemistry
Catalysis
Organic Chemistry

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10.1002/chem.201103325

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abstract = "Polyene synthesis: An efficient approach to the total synthesis of polyene natural product dihydroxrulin (1) is described. A novel, mild, direct organocatalytic IBX-mediated dehydrogenation process of simple alcohols to enals has been developed, which serves as a key step in the synthesis (see scheme).",

keywords = "dehydrogenation, dihydroxerulin, enals, organocatalysis, oxidative enamine catalysis, polyenes",

author = "Hexin Xie and Shilei Zhang and Hao Li and Xinshuai Zhang and Sihan Zhao and Zian Xu and Xixi Song and Xinhong Yu and Wei Wang",

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T1 - Total synthesis of polyene natural product dihydroxerulin by mild organocatalyzed dehydrogenation of alcohols

AU - Xie, Hexin

AU - Zhang, Shilei

AU - Li, Hao

AU - Zhang, Xinshuai

AU - Zhao, Sihan

AU - Xu, Zian

AU - Song, Xixi

AU - Yu, Xinhong

AU - Wang, Wei

PY - 2012/2/20

Y1 - 2012/2/20

N2 - Polyene synthesis: An efficient approach to the total synthesis of polyene natural product dihydroxrulin (1) is described. A novel, mild, direct organocatalytic IBX-mediated dehydrogenation process of simple alcohols to enals has been developed, which serves as a key step in the synthesis (see scheme).

AB - Polyene synthesis: An efficient approach to the total synthesis of polyene natural product dihydroxrulin (1) is described. A novel, mild, direct organocatalytic IBX-mediated dehydrogenation process of simple alcohols to enals has been developed, which serves as a key step in the synthesis (see scheme).

KW - dehydrogenation

KW - dihydroxerulin

KW - enals

KW - organocatalysis

KW - oxidative enamine catalysis

KW - polyenes

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EP - 2234

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 8

ER -

Total synthesis of polyene natural product dihydroxerulin by mild organocatalyzed dehydrogenation of alcohols

Abstract

Keywords

ASJC Scopus subject areas

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