Total artificial heart implantation in a young marfan syndrome patient

Prashant Rao, Jack B. Keenan, Taufiek K. Rajab, Samuel Kim, Richard Smith, Orazio Amabile, Zain Khalpey

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Introduction: Cardiovascular complications represent the leading cause of morbidity and mortality in patients with Marfan syndrome. Here, we describe a unique case where a total artificial heart was implanted in a young Marfan syndrome woman. Methods: A 22-year-old postpartum African American female with Marfan syndrome developed multiple severe valve dysfunction and biventricular failure that was refractory to medical management. She previously had a Bentall procedure for Type A aortic dissection and repair of a Type B dissection. Results: We implanted a total artificial heart with a good outcome. Conclusion: Total artificial heart is a durable option for severe biventricular failure and multiple valvular dysfunction as a bridge to transplant in a young patient with Marfan syndrome.

Original languageEnglish (US)
Pages (from-to)175-177
Number of pages3
JournalInternational Journal of Artificial Organs
Issue number3
StatePublished - 2018


  • Bridge to transplant
  • Marfan syndrome
  • Total artificial heart

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering


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