TORCing Neutrophil Chemotaxis

Pascale G. Charest, Richard A. Firtel

Research output: Contribution to journalShort surveypeer-review

5 Scopus citations


During cell migration, chemoattractant-induced signaling pathways determine the direction of movement by controlling the spatiotemporal dynamics of cytoskeletal components. In this issue of Developmental Cell, Liu et al. report that the target of rapamycin complex 2 (TORC2) controls cell polarity and chemotaxis through regulation of both F-actin and myosin II in migrating neutrophils.

Original languageEnglish (US)
Pages (from-to)795-796
Number of pages2
JournalDevelopmental Cell
Issue number6
StatePublished - Dec 14 2010

ASJC Scopus subject areas

  • Molecular Biology
  • General Biochemistry, Genetics and Molecular Biology
  • Developmental Biology
  • Cell Biology


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