Top-Down Systematic Approach to Interpretation of FDG-PET for Dementia

David M. Sawyer, Phillip H Kuo

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Dementia is an important cause of morbidity and mortality worldwide and encompasses a very heterogenous group of disease processes. Positron emission tomography (PET) of the brain using fluorodeoxyglucose (FDG) is a useful modality for differentiating types of dementia. Because FDG does not bind to pathologic proteins, FDG-PET requires that the reader recognize characteristic patterns of glucose hypometabolism to identify pathology. These patterns have been documented in the literature for both primary neurodegenerative disorders and secondary causes of dementia. This article presents an algorithm for organizing these findings and systematically applying them to interpret FDG-PET brain imaging for dementia.

Original languageEnglish (US)
Pages (from-to)e212-e214
JournalClinical nuclear medicine
Issue number6
StatePublished - Jun 1 2018


  • algorithm
  • dementia

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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