Tocainide for refractory ventricular arrhythmias of myocardial infarction

Charles I. Haffajee, Joseph S. Alpert, James E. Dalen

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Oral tocainide was used as a long-term antiarrhythmic in patients with symptomatic high-grade ventricular ectopic activity refractory to conventional antiarrhythmic agents. Eleven of the 22 patients had a previous myocardial infarction (three patients had a ventricular aneurysm). Unacceptable side effects precluded long-term use of tocainide in two patients. Long-term tocainide was effective in six of the remaining patients for periods of 9 days to 42.5 months (mean 15.2 months). Eight of these nine patients responded to intravenous lidocaine prior to tocainide therapy.

Original languageEnglish (US)
Pages (from-to)1013-1016
Number of pages4
JournalAmerican Heart Journal
Issue number6 PART 2
StatePublished - Dec 1980

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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