Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: A mechanism for the functional loss of PTEN's tumor suppressor activity

Emmanuelle J. Meuillet, Daruka Mahadevan, Margareta Berggren, Amy Coon, Garth Powis

Research output: Contribution to journal › Article › peer-review

172 Scopus citations

Fingerprint

Dive into the research topics of 'Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: A mechanism for the functional loss of PTEN's tumor suppressor activity'. Together they form a unique fingerprint.

Keyphrases

Biochemistry, Genetics and Molecular Biology