TY - JOUR
T1 - Think globally, act locally
T2 - Centrosome-localized mRNAs ensure mitotic fidelity
AU - Zarnescu, Daniela C.
N1 - Publisher Copyright:
© 2020 Zarnescu.
PY - 2020/12/7
Y1 - 2020/12/7
N2 - The functional importance of mRNA localization to centrosomes is unclear. Ryder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202004101) identify fragile-X mental retardation protein as a regulator of centrocortin (cen) mRNA dynamics in Drosophila. Mistargeting of cen impairs division and development, indicating that cen mRNA localization to centrosomes ensures mitotic fidelity.
AB - The functional importance of mRNA localization to centrosomes is unclear. Ryder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202004101) identify fragile-X mental retardation protein as a regulator of centrocortin (cen) mRNA dynamics in Drosophila. Mistargeting of cen impairs division and development, indicating that cen mRNA localization to centrosomes ensures mitotic fidelity.
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U2 - 10.1083/JCB.202010172
DO - 10.1083/JCB.202010172
M3 - Article
C2 - 33216116
AN - SCOPUS:85096814395
SN - 0021-9525
VL - 219
JO - Journal of Cell Biology
JF - Journal of Cell Biology
IS - 12
M1 - e202010172
ER -