Abstract
A strategy for the total synthesis of vinigrol is detailed with two key steps - oxidative dearomatization and intramolecular Diels-Alder cycloaddition - providing the cis-decalin core. A novel and mild means for the formation of ortho-quinone methides is also described.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 23-27 |
| Number of pages | 5 |
| Journal | Synlett |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2009 |
| Externally published | Yes |
Keywords
- Cycloaddition
- Oxidative dearomatization
- Trichloroacetylisocyanate
- Vinigrol
- ortho-quinone methide
ASJC Scopus subject areas
- Organic Chemistry