Thieme Chemistry Journal awardees - Where are they now? Efforts towards the total synthesis of vinigrol

Jason G.M. Morton; Laura D. Kwon; John D. Freeman; Jon T. Njardarson

doi:10.1055/s-0028-1087378

Thieme Chemistry Journal awardees - Where are they now? Efforts towards the total synthesis of vinigrol

Jason G.M. Morton, Laura D. Kwon, John D. Freeman, Jon T. Njardarson

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

A strategy for the total synthesis of vinigrol is detailed with two key steps - oxidative dearomatization and intramolecular Diels-Alder cycloaddition - providing the cis-decalin core. A novel and mild means for the formation of ortho-quinone methides is also described.

Original language	English (US)
Pages (from-to)	23-27
Number of pages	5
Journal	Synlett
Issue number	1
DOIs	https://doi.org/10.1055/s-0028-1087378
State	Published - Jan 2009
Externally published	Yes

Keywords

Cycloaddition
Oxidative dearomatization
Trichloroacetylisocyanate
Vinigrol
ortho-quinone methide

ASJC Scopus subject areas

Organic Chemistry

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10.1055/s-0028-1087378

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abstract = "A strategy for the total synthesis of vinigrol is detailed with two key steps - oxidative dearomatization and intramolecular Diels-Alder cycloaddition - providing the cis-decalin core. A novel and mild means for the formation of ortho-quinone methides is also described.",

keywords = "Cycloaddition, Oxidative dearomatization, Trichloroacetylisocyanate, Vinigrol, ortho-quinone methide",

author = "Morton, {Jason G.M.} and Kwon, {Laura D.} and Freeman, {John D.} and Njardarson, {Jon T.}",

year = "2009",

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AU - Kwon, Laura D.

AU - Freeman, John D.

AU - Njardarson, Jon T.

PY - 2009/1

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AB - A strategy for the total synthesis of vinigrol is detailed with two key steps - oxidative dearomatization and intramolecular Diels-Alder cycloaddition - providing the cis-decalin core. A novel and mild means for the formation of ortho-quinone methides is also described.

KW - Cycloaddition

KW - Oxidative dearomatization

KW - Trichloroacetylisocyanate

KW - Vinigrol

KW - ortho-quinone methide

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Thieme Chemistry Journal awardees - Where are they now? Efforts towards the total synthesis of vinigrol

Abstract

Keywords

ASJC Scopus subject areas

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