THICKNESS and STIFFNESS ADAPTATIONS of the TRANSVERSE CARPAL LIGAMENT ASSOCIATED with CARPAL TUNNEL SYNDROME

Tamara L. Marquardt; Joseph N. Gabra; Peter J. Evans; William H. Seitz; Zong Ming Li

doi:10.1142/S0218957716500196

THICKNESS and STIFFNESS ADAPTATIONS of the TRANSVERSE CARPAL LIGAMENT ASSOCIATED with CARPAL TUNNEL SYNDROME

Tamara L. Marquardt, Joseph N. Gabra, Peter J. Evans, William H. Seitz, Zong Ming Li

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The purpose of this study was to investigate the morphological and mechanical properties of the transverse carpal ligament (TCL) in patients with carpal tunnel syndrome (CTS). Thickness and stiffness of the TCL in eight female CTS patients and eight female control subjects were examined using ultrasound imaging modalities. CTS patients had a 30.9% thicker TCL than control subjects. There was no overall difference in TCL stiffness between the two groups, but the radial TCL region was significantly stiffer than the ulnar region within the CTS group and such a regional difference was not found for the controls. The increased thickness and localized stiffness of the TCL for CTS patients may contribute to CTS symptoms due to reduction in carpal tunnel space and compliance. Advancements in ultrasound technology provide a means of understanding CTS mechanisms and quantifying the morphological and mechanical properties of the TCL in vivo.

Original language	English (US)
Article number	1650019
Journal	Journal of Musculoskeletal Research
Volume	19
Issue number	4
DOIs	https://doi.org/10.1142/S0218957716500196
State	Published - Dec 1 2016
Externally published	Yes

Keywords

Acoustic radiation force impulse
Carpal tunnel syndrome
Transverse carpal ligament
Ultrasound imaging

ASJC Scopus subject areas

Orthopedics and Sports Medicine

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title = "THICKNESS and STIFFNESS ADAPTATIONS of the TRANSVERSE CARPAL LIGAMENT ASSOCIATED with CARPAL TUNNEL SYNDROME",

abstract = "The purpose of this study was to investigate the morphological and mechanical properties of the transverse carpal ligament (TCL) in patients with carpal tunnel syndrome (CTS). Thickness and stiffness of the TCL in eight female CTS patients and eight female control subjects were examined using ultrasound imaging modalities. CTS patients had a 30.9% thicker TCL than control subjects. There was no overall difference in TCL stiffness between the two groups, but the radial TCL region was significantly stiffer than the ulnar region within the CTS group and such a regional difference was not found for the controls. The increased thickness and localized stiffness of the TCL for CTS patients may contribute to CTS symptoms due to reduction in carpal tunnel space and compliance. Advancements in ultrasound technology provide a means of understanding CTS mechanisms and quantifying the morphological and mechanical properties of the TCL in vivo.",

keywords = "Acoustic radiation force impulse, Carpal tunnel syndrome, Transverse carpal ligament, Ultrasound imaging",

author = "Marquardt, {Tamara L.} and Gabra, {Joseph N.} and Evans, {Peter J.} and Seitz, {William H.} and Li, {Zong Ming}",

note = "Funding Information: Research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number R21AR064957 (ZML). Publisher Copyright: {\textcopyright} 2016 World Scientific Publishing Company.",

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AU - Marquardt, Tamara L.

AU - Gabra, Joseph N.

AU - Evans, Peter J.

AU - Seitz, William H.

AU - Li, Zong Ming

N1 - Funding Information: Research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number R21AR064957 (ZML). Publisher Copyright: © 2016 World Scientific Publishing Company.

PY - 2016/12/1

Y1 - 2016/12/1

N2 - The purpose of this study was to investigate the morphological and mechanical properties of the transverse carpal ligament (TCL) in patients with carpal tunnel syndrome (CTS). Thickness and stiffness of the TCL in eight female CTS patients and eight female control subjects were examined using ultrasound imaging modalities. CTS patients had a 30.9% thicker TCL than control subjects. There was no overall difference in TCL stiffness between the two groups, but the radial TCL region was significantly stiffer than the ulnar region within the CTS group and such a regional difference was not found for the controls. The increased thickness and localized stiffness of the TCL for CTS patients may contribute to CTS symptoms due to reduction in carpal tunnel space and compliance. Advancements in ultrasound technology provide a means of understanding CTS mechanisms and quantifying the morphological and mechanical properties of the TCL in vivo.

AB - The purpose of this study was to investigate the morphological and mechanical properties of the transverse carpal ligament (TCL) in patients with carpal tunnel syndrome (CTS). Thickness and stiffness of the TCL in eight female CTS patients and eight female control subjects were examined using ultrasound imaging modalities. CTS patients had a 30.9% thicker TCL than control subjects. There was no overall difference in TCL stiffness between the two groups, but the radial TCL region was significantly stiffer than the ulnar region within the CTS group and such a regional difference was not found for the controls. The increased thickness and localized stiffness of the TCL for CTS patients may contribute to CTS symptoms due to reduction in carpal tunnel space and compliance. Advancements in ultrasound technology provide a means of understanding CTS mechanisms and quantifying the morphological and mechanical properties of the TCL in vivo.

KW - Acoustic radiation force impulse

KW - Carpal tunnel syndrome

KW - Transverse carpal ligament

KW - Ultrasound imaging

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THICKNESS and STIFFNESS ADAPTATIONS of the TRANSVERSE CARPAL LIGAMENT ASSOCIATED with CARPAL TUNNEL SYNDROME

Abstract

Keywords

ASJC Scopus subject areas

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