Therapeutic potential of various plant-based fibers to improve energy homeostasis via the gut microbiota

Taylor M. Martinez, Rachel K. Meyer, Frank A. Duca

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Obesity is due in part to increased consumption of a Western diet that is low in dietary fiber. Conversely, an increase in fiber supplementation to a diet can have various beneficial effects on metabolic homeostasis including weight loss and reduced adiposity. Fibers are extremely diverse in source and composition, such as high-amylose maize, β-glucan, wheat fiber, pectin, inulin-type fructans, and soluble corn fiber. Despite the heterogeneity of dietary fiber, most have been shown to play a role in alleviating obesity-related health issues, mainly by targeting and utilizing the properties of the gut microbiome. Reductions in body weight, adiposity, food intake, and markers of inflammation have all been reported with the consumption of various fibers, making them a promising treatment option for the obesity epidemic. This review will highlight the current findings on different plant-based fibers as a therapeutic dietary supplement to improve energy homeostasis via mechanisms of gut microbiota.

Original languageEnglish (US)
Article number3470
Issue number10
StatePublished - Oct 2021


  • Dietary fiber
  • Energy homeostasis
  • Gut microbiome
  • Obesity

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics


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