Theoretical and empirical characterization of the physical characteristics of a clinical digital mammography system

Sankararaman Suryanarayanan, Andrew Karellas, Srinivasan Vedantham, Hetal Ved, Carl J. D'Orsi

Research output: Contribution to journalConference articlepeer-review

3 Scopus citations


The physical performance characteristics of a clinical full-field digital mammography (FFDM) system were analyzed for different target/filter conditions using theoretical modeling and experimental measurements. The signal and noise propagation through the various stages of the FFDM system was simulated as a cascaded process and used to compute the frequency dependent detective quantum efficiency (DQE) of the system. The presampling modulation transfer function (MTF) of the system and the noise power spectra (NPS) of the system were measured under the different spectral conditions as used in the theoretical model at an exposure close to 10-mR from which corresponding DQEs were computed. The experimental zero frequency DQE after filtering the x-ray beam through 45-mm acrylic was estimated at 0.51, 0.48, and 0.46 for Mo/Mo, Mo/Rh, and Rh/Rh respectively. A good agreement between the theoretical and experimental results was observed. The clinical digital mammography system appears to exhibit favorable physical characteristics and similar models could be used to design and optimize other imaging systems.

Original languageEnglish (US)
Pages (from-to)929-938
Number of pages10
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5030 II
StatePublished - 2003
EventMedical Imaging 2003: Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 16 2003Feb 18 2003


  • Amorphous silicon
  • Breast cancer
  • Detective quantum efficiency
  • Digital mammography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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