Abstract
Background:The role of Foxf1 in smooth muscle development is unknown. Results:Foxf1 binds to serum response factor and myocardin to regulate transcription and affect contractility of visceral smooth muscle cells. Conclusion:Foxf1 is required for normal development of gastrointestinal smooth muscle. Significance:Forkhead proteins interact with the SRF/myocardin axis to control the phenotype of smooth muscle cells.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 28477-28487 |
| Number of pages | 11 |
| Journal | Journal of Biological Chemistry |
| Volume | 288 |
| Issue number | 40 |
| DOIs | |
| State | Published - Oct 4 2013 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Cell Biology
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