Abstract
Two structurally unique organocesium carbanionic tetramic acids have been synthesized through expeditious and novel cascade reactions of strategically functionalized Ugi skeletons delivering products with two points of potential diversification. This is the first report of the use of multicomponent reactions and subsequent cascades to access complex, unprecedented organocesium architectures. Moreover, this article also highlights the first use of mild cesium carbonate as a cesium source for the construction of cesium organometallic scaffolds. Relativistic DFT calculations provide an insight into the electronic structure of the reported compounds. Cascades, cesium, and complexity: Two structurally unique organocesium carbanionic tetramic acids have been synthesized through expeditious and novel cascade reactions of strategically functionalized Ugi skeletons delivering products with two points of potential diversification. This is the first report of the use of multicomponent reactions and subsequent cascades to access unprecedented complex organocesium architectures.
Original language | English (US) |
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Pages (from-to) | 11672-11676 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 54 |
Issue number | 40 |
DOIs | |
State | Published - Sep 1 2015 |
Keywords
- Dieckmann condensation
- Ugi reaction
- cascade reactions
- multicomponent reactions
- tetramic acids
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
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CCDC 1052075: Experimental Crystal Structure Determination
Martinez-Ariza, G. (Creator), Ayaz, M. (Creator), Roberts, S. A. (Creator), Rabanal-Leõn, W. A. (Contributor), Arratia-Pérez, R. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc149rx3, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc149rx3&sid=DataCite
Dataset
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CCDC 1052077: Experimental Crystal Structure Determination
Martinez-Ariza, G. (Creator), Ayaz, M. (Creator), Roberts, S. A. (Creator), Rabanal-Leõn, W. A. (Contributor), Arratia-Pérez, R. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc149rz5, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc149rz5&sid=DataCite
Dataset
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CCDC 1052076: Experimental Crystal Structure Determination
Martinez-Ariza, G. (Creator), Ayaz, M. (Creator), Roberts, S. A. (Creator), Rabanal-Leõn, W. A. (Contributor), Arratia-Pérez, R. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc149ry4, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc149ry4&sid=DataCite
Dataset