The sexually dimorphic region of the preoptic area in rats contains denser opiate receptor binding sites in females

Ronald P. Hammer

doi:10.1016/0006-8993(84)90932-6

The sexually dimorphic region of the preoptic area in rats contains denser opiate receptor binding sites in females

Ronald P. Hammer

Research output: Contribution to journal › Article › peer-review

99 Scopus citations

Abstract

Quantitative autoradiographic analysis of opiate receptor binding using [³H]naloxone shows higher levels in the sexually dimorphic region of the medial preoptic area in female rats than in males. Opiate receptor density varies across the estrous cycle being densest in diestrous females. The sexually dimorphic nucleus of the preoptic are lies within the opiate receptor-rich region. Endogenous opiates in the medial preoptic region acting at opiate receptors which are of differential density in males and females could influence sex-specific behavior mediated by the region.

Original language	English (US)
Pages (from-to)	172-176
Number of pages	5
Journal	Brain Research
Volume	308
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(84)90932-6
State	Published - Aug 6 1984
Externally published	Yes

Keywords

estrous stages
medial preoptic area
opiate receptors
sexual dimorphism

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(84)90932-6

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abstract = "Quantitative autoradiographic analysis of opiate receptor binding using [3H]naloxone shows higher levels in the sexually dimorphic region of the medial preoptic area in female rats than in males. Opiate receptor density varies across the estrous cycle being densest in diestrous females. The sexually dimorphic nucleus of the preoptic are lies within the opiate receptor-rich region. Endogenous opiates in the medial preoptic region acting at opiate receptors which are of differential density in males and females could influence sex-specific behavior mediated by the region.",

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AU - Hammer, Ronald P.

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N2 - Quantitative autoradiographic analysis of opiate receptor binding using [3H]naloxone shows higher levels in the sexually dimorphic region of the medial preoptic area in female rats than in males. Opiate receptor density varies across the estrous cycle being densest in diestrous females. The sexually dimorphic nucleus of the preoptic are lies within the opiate receptor-rich region. Endogenous opiates in the medial preoptic region acting at opiate receptors which are of differential density in males and females could influence sex-specific behavior mediated by the region.

AB - Quantitative autoradiographic analysis of opiate receptor binding using [3H]naloxone shows higher levels in the sexually dimorphic region of the medial preoptic area in female rats than in males. Opiate receptor density varies across the estrous cycle being densest in diestrous females. The sexually dimorphic nucleus of the preoptic are lies within the opiate receptor-rich region. Endogenous opiates in the medial preoptic region acting at opiate receptors which are of differential density in males and females could influence sex-specific behavior mediated by the region.

KW - estrous stages

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KW - opiate receptors

KW - sexual dimorphism

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The sexually dimorphic region of the preoptic area in rats contains denser opiate receptor binding sites in females

Abstract

Keywords

ASJC Scopus subject areas

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