The septins: Roles in cytokinesis and other processes

Mark S. Longtine, Douglas J. DeMarini, Maria L. Valencik, Omayma S. Al-Awar, Hanna Fares, Claudio De Virgilio, John R. Pringle

Research output: Contribution to journalArticlepeer-review

418 Scopus citations


The septins are a novel family of proteins that were first recognized in yeast as proteins associated with the neck filaments. Recent work has shown that septins are also present in other fungi, insects, and vertebrates. Despite the apparent differences in modes of cytokinesis amongst species, septins appear to be essential for this process in both fungal and animal cells. The septins also appear to be involved in various other aspects of the organization of the cell surface.

Original languageEnglish (US)
Pages (from-to)106-119
Number of pages14
JournalCurrent Opinion in Cell Biology
Issue number1
StatePublished - Feb 1996

ASJC Scopus subject areas

  • Cell Biology


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