The second space experiment of protein crystallization with domestic facilities

Yaoping Wang; Jishen Pan; Xiutian Niu; Yuancong Zhou; Ziqian Hua; Qian Xu; Shen Wu; Qing Han; Hongmin Li; Yanshun Liu; Maikun Teng; Haihui He; Shengxiang Lin; Ruchang Bi

The second space experiment of protein crystallization with domestic facilities

Yaoping Wang, Jishen Pan, Xiutian Niu, Yuancong Zhou, Ziqian Hua, Qian Xu, Shen Wu, Qing Han, Hongmin Li, Yanshun Liu, Maikun Teng, Haihui He, Shengxiang Lin, Ruchang Bi

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The second experiment of protein crystallization was performed on domestic re-entry satellite FSW-2 in 1994-07. The results are superior to the ones of the first mission in 1992: 9 of 10 different proteins were crystallized in space, and 70% of the total 48 samples yielded single crystals. Besides hen egg-white lysozyme which grew high-quality crystals on the first mission, an acidic phospholipase A₂(aPLA₂) from snake venom and hemoglobin from Anser Indicus produced good-quality crystals suitable for X-ray diffraction analyses. The positive effect of microgravity on protein crystal growth is verified again at this time.

Original language	English (US)
Pages (from-to)	458-464
Number of pages	7
Journal	Science in China, Series C: Life Sciences
Volume	39
Issue number	5
State	Published - Oct 1996
Externally published	Yes

Keywords

Crystal growth
Microgravity
Protein

ASJC Scopus subject areas

Renewable Energy, Sustainability and the Environment
Modeling and Simulation
General Biochemistry, Genetics and Molecular Biology
Fuel Technology
General Environmental Science
Energy Engineering and Power Technology
General Agricultural and Biological Sciences
General Energy
Management, Monitoring, Policy and Law

Cite this

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title = "The second space experiment of protein crystallization with domestic facilities",

abstract = "The second experiment of protein crystallization was performed on domestic re-entry satellite FSW-2 in 1994-07. The results are superior to the ones of the first mission in 1992: 9 of 10 different proteins were crystallized in space, and 70% of the total 48 samples yielded single crystals. Besides hen egg-white lysozyme which grew high-quality crystals on the first mission, an acidic phospholipase A2(aPLA2) from snake venom and hemoglobin from Anser Indicus produced good-quality crystals suitable for X-ray diffraction analyses. The positive effect of microgravity on protein crystal growth is verified again at this time.",

keywords = "Crystal growth, Microgravity, Protein",

author = "Yaoping Wang and Jishen Pan and Xiutian Niu and Yuancong Zhou and Ziqian Hua and Qian Xu and Shen Wu and Qing Han and Hongmin Li and Yanshun Liu and Maikun Teng and Haihui He and Shengxiang Lin and Ruchang Bi",

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T1 - The second space experiment of protein crystallization with domestic facilities

AU - Wang, Yaoping

AU - Pan, Jishen

AU - Niu, Xiutian

AU - Zhou, Yuancong

AU - Hua, Ziqian

AU - Xu, Qian

AU - Wu, Shen

AU - Han, Qing

AU - Li, Hongmin

AU - Liu, Yanshun

AU - Teng, Maikun

AU - He, Haihui

AU - Lin, Shengxiang

AU - Bi, Ruchang

PY - 1996/10

Y1 - 1996/10

N2 - The second experiment of protein crystallization was performed on domestic re-entry satellite FSW-2 in 1994-07. The results are superior to the ones of the first mission in 1992: 9 of 10 different proteins were crystallized in space, and 70% of the total 48 samples yielded single crystals. Besides hen egg-white lysozyme which grew high-quality crystals on the first mission, an acidic phospholipase A2(aPLA2) from snake venom and hemoglobin from Anser Indicus produced good-quality crystals suitable for X-ray diffraction analyses. The positive effect of microgravity on protein crystal growth is verified again at this time.

AB - The second experiment of protein crystallization was performed on domestic re-entry satellite FSW-2 in 1994-07. The results are superior to the ones of the first mission in 1992: 9 of 10 different proteins were crystallized in space, and 70% of the total 48 samples yielded single crystals. Besides hen egg-white lysozyme which grew high-quality crystals on the first mission, an acidic phospholipase A2(aPLA2) from snake venom and hemoglobin from Anser Indicus produced good-quality crystals suitable for X-ray diffraction analyses. The positive effect of microgravity on protein crystal growth is verified again at this time.

KW - Crystal growth

KW - Microgravity

KW - Protein

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JF - Science in China, Series C: Life Sciences

IS - 5

ER -

The second space experiment of protein crystallization with domestic facilities

Abstract

Keywords

ASJC Scopus subject areas

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