The Safety on the TCR Trigger

Michael S. Kuhns; Mark M. Davis

doi:10.1016/j.cell.2008.10.033

The Safety on the TCR Trigger

Michael S. Kuhns, Mark M. Davis

Research output: Contribution to journal › Short survey › peer-review

40 Scopus citations

Abstract

In this issue, Xu et al. (2008) provide evidence for a new mechanism of T cell receptor regulation. Prior to activation, basic residues in the cytoplasmic domain of the signaling subunits of the T cell receptor associate with the plasma membrane such that the key signaling tyrosines are sequestered in the bilayer.

Original language	English (US)
Pages (from-to)	594-596
Number of pages	3
Journal	Cell
Volume	135
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2008.10.033
State	Published - Nov 14 2008

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Access to Document

10.1016/j.cell.2008.10.033

Cite this

@article{137a3ab8b2774d22b1d8164860ecc8ac,

title = "The Safety on the TCR Trigger",

abstract = "In this issue, Xu et al. (2008) provide evidence for a new mechanism of T cell receptor regulation. Prior to activation, basic residues in the cytoplasmic domain of the signaling subunits of the T cell receptor associate with the plasma membrane such that the key signaling tyrosines are sequestered in the bilayer.",

author = "Kuhns, {Michael S.} and Davis, {Mark M.}",

year = "2008",

month = nov,

day = "14",

doi = "10.1016/j.cell.2008.10.033",

language = "English (US)",

volume = "135",

pages = "594--596",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - The Safety on the TCR Trigger

AU - Kuhns, Michael S.

AU - Davis, Mark M.

PY - 2008/11/14

Y1 - 2008/11/14

N2 - In this issue, Xu et al. (2008) provide evidence for a new mechanism of T cell receptor regulation. Prior to activation, basic residues in the cytoplasmic domain of the signaling subunits of the T cell receptor associate with the plasma membrane such that the key signaling tyrosines are sequestered in the bilayer.

AB - In this issue, Xu et al. (2008) provide evidence for a new mechanism of T cell receptor regulation. Prior to activation, basic residues in the cytoplasmic domain of the signaling subunits of the T cell receptor associate with the plasma membrane such that the key signaling tyrosines are sequestered in the bilayer.

UR - http://www.scopus.com/inward/record.url?scp=55449093482&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=55449093482&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2008.10.033

DO - 10.1016/j.cell.2008.10.033

M3 - Short survey

C2 - 19013269

AN - SCOPUS:55449093482

VL - 135

SP - 594

EP - 596

JO - Cell

JF - Cell

SN - 0092-8674

IS - 4

ER -

The Safety on the TCR Trigger

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this