The Safety on the TCR Trigger

Michael S. Kuhns; Mark M. Davis

doi:10.1016/j.cell.2008.10.033

The Safety on the TCR Trigger

Michael S. Kuhns, Mark M. Davis

Research output: Contribution to journal › Short survey › peer-review

41 Scopus citations

Abstract

In this issue, Xu et al. (2008) provide evidence for a new mechanism of T cell receptor regulation. Prior to activation, basic residues in the cytoplasmic domain of the signaling subunits of the T cell receptor associate with the plasma membrane such that the key signaling tyrosines are sequestered in the bilayer.

Original language	English (US)
Pages (from-to)	594-596
Number of pages	3
Journal	Cell
Volume	135
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2008.10.033
State	Published - Nov 14 2008

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/j.cell.2008.10.033

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title = "The Safety on the TCR Trigger",

abstract = "In this issue, Xu et al. (2008) provide evidence for a new mechanism of T cell receptor regulation. Prior to activation, basic residues in the cytoplasmic domain of the signaling subunits of the T cell receptor associate with the plasma membrane such that the key signaling tyrosines are sequestered in the bilayer.",

author = "Kuhns, {Michael S.} and Davis, {Mark M.}",

year = "2008",

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AU - Kuhns, Michael S.

AU - Davis, Mark M.

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AB - In this issue, Xu et al. (2008) provide evidence for a new mechanism of T cell receptor regulation. Prior to activation, basic residues in the cytoplasmic domain of the signaling subunits of the T cell receptor associate with the plasma membrane such that the key signaling tyrosines are sequestered in the bilayer.

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SP - 594

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JO - Cell

JF - Cell

SN - 0092-8674

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The Safety on the TCR Trigger

Abstract

ASJC Scopus subject areas

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