Abstract
Autophagy is a catabolic process that has been shown to have a role in many cellular processes including the removal of excessive or damaged proteins and protein aggregates. The salivary glands play a critical role in oral health, and their secretory capacity may be critically intertwined with the autophagic process. This review describes the role of autophagy activation in normal salivary gland homeostasis and during the glandular stress responses of therapeutic radiation, ductal ligation, autoimmunity, and salivary gland adenoid cystic carcinoma.
Original language | English (US) |
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Pages (from-to) | 1035-1040 |
Number of pages | 6 |
Journal | Journal of Dental Research |
Volume | 94 |
Issue number | 8 |
DOIs | |
State | Published - Aug 25 2015 |
Keywords
- Sjogren's syndrome
- cancer
- ductal ligation
- radiation
- rapalogues
- salivary physiology
ASJC Scopus subject areas
- General Dentistry