The return of delayed-type hypersensitivity skin testing for coccidioidomycosis

Elizabeth E. Wack, Neil M. Ampel, Rebecca H. Sunenshine, John N. Galgiani

Research output: Contribution to journalReview articlepeer-review

39 Scopus citations


A skin test that detects dermal hypersensitivity in persons with past infection with Coccidioides species is again available for clinical use. Nearly all of the clinical studies with similar materials were published prior to the 1990s, and as a result, many practicing physicians will be unfamiliar with how skin testing for coccidioidomycosis might be useful in patient management or as a research tool.We review clinical and epidemiological studies with past skin test antigens, the composition of past and current skin test preparations with particular attention to differences in the preservatives, and how the current preparation could be used today.

Original languageEnglish (US)
Pages (from-to)787-791
Number of pages5
JournalClinical Infectious Diseases
Issue number5
StatePublished - Sep 1 2015


  • Cellular immunity
  • Coccidioidomycosis
  • Delayed type hypersensitivity
  • Diagnostic test
  • Skin test

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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