The return of delayed-type hypersensitivity skin testing for coccidioidomycosis

Elizabeth E. Wack; Neil M. Ampel; Rebecca H. Sunenshine; John N. Galgiani

doi:10.1093/cid/civ388

The return of delayed-type hypersensitivity skin testing for coccidioidomycosis

Elizabeth E. Wack, Neil M. Ampel, Rebecca H. Sunenshine, John N. Galgiani

Research output: Contribution to journal › Review article › peer-review

41 Scopus citations

Abstract

A skin test that detects dermal hypersensitivity in persons with past infection with Coccidioides species is again available for clinical use. Nearly all of the clinical studies with similar materials were published prior to the 1990s, and as a result, many practicing physicians will be unfamiliar with how skin testing for coccidioidomycosis might be useful in patient management or as a research tool.We review clinical and epidemiological studies with past skin test antigens, the composition of past and current skin test preparations with particular attention to differences in the preservatives, and how the current preparation could be used today.

Original language	English (US)
Pages (from-to)	787-791
Number of pages	5
Journal	Clinical Infectious Diseases
Volume	61
Issue number	5
DOIs	https://doi.org/10.1093/cid/civ388
State	Published - Sep 1 2015

Keywords

Cellular immunity
Coccidioidomycosis
Delayed type hypersensitivity
Diagnostic test
Skin test

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1093/cid/civ388

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abstract = "A skin test that detects dermal hypersensitivity in persons with past infection with Coccidioides species is again available for clinical use. Nearly all of the clinical studies with similar materials were published prior to the 1990s, and as a result, many practicing physicians will be unfamiliar with how skin testing for coccidioidomycosis might be useful in patient management or as a research tool.We review clinical and epidemiological studies with past skin test antigens, the composition of past and current skin test preparations with particular attention to differences in the preservatives, and how the current preparation could be used today.",

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AB - A skin test that detects dermal hypersensitivity in persons with past infection with Coccidioides species is again available for clinical use. Nearly all of the clinical studies with similar materials were published prior to the 1990s, and as a result, many practicing physicians will be unfamiliar with how skin testing for coccidioidomycosis might be useful in patient management or as a research tool.We review clinical and epidemiological studies with past skin test antigens, the composition of past and current skin test preparations with particular attention to differences in the preservatives, and how the current preparation could be used today.

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The return of delayed-type hypersensitivity skin testing for coccidioidomycosis

Abstract

Keywords

ASJC Scopus subject areas

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