The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile

Li Fang Yu, J. Brek Eaton, Han Kun Zhang, Emily Sabath, Taleen Hanania, Guan Nan Li, Richard B. van Breemen, Paul Whiteaker, Qiang Liu, Jie Wu, Yong Chang Chang, Ronald J. Lukas, Dani Brunner, Alan P. Kozikowski

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Pharmacology, Toxicology and Pharmaceutical Science