TY - JOUR
T1 - The Papillomavirus Episteme
T2 - A central resource for papillomavirus sequence data and analysis
AU - Van Doorslaer, Koenraad
AU - Tan, Qina
AU - Xirasagar, Sandhya
AU - Bandaru, Sandya
AU - Gopalan, Vivek
AU - Mohamoud, Yasmin
AU - Huyen, Yentram
AU - McBride, Alison A.
N1 - Funding Information:
The Intramural Research Program [1ZIAAI001071] and Office of Science Management and Operations of the National Institutes of Allergy and Infectious Diseases, National Institutes of Health. Funding for open access charge: NIAID Intramural Research Program [1ZIAAI001071].
PY - 2013/1/1
Y1 - 2013/1/1
N2 - The goal of the Papillomavirus Episteme (PaVE) is to provide an integrated resource for the analysis of papillomavirus (PV) genome sequences and related information. The PaVE is a freely accessible, web-based tool (http://pave.niaid.nih.gov) created around a relational database, which enables storage, analysis and exchange of sequence information. From a design perspective, the PaVE adopts an Open Source software approach and stresses the integration and reuse of existing tools. Reference PV genome sequences have been extracted from publicly available databases and reannotated using a custom-created tool. To date, the PaVE contains 241 annotated PV genomes, 2245 genes and regions, 2004 protein sequences and 47 protein structures, which users can explore, analyze or download. The PaVE provides scientists with the data and tools needed to accelerate scientific progress for the study and treatment of diseases caused by PVs.
AB - The goal of the Papillomavirus Episteme (PaVE) is to provide an integrated resource for the analysis of papillomavirus (PV) genome sequences and related information. The PaVE is a freely accessible, web-based tool (http://pave.niaid.nih.gov) created around a relational database, which enables storage, analysis and exchange of sequence information. From a design perspective, the PaVE adopts an Open Source software approach and stresses the integration and reuse of existing tools. Reference PV genome sequences have been extracted from publicly available databases and reannotated using a custom-created tool. To date, the PaVE contains 241 annotated PV genomes, 2245 genes and regions, 2004 protein sequences and 47 protein structures, which users can explore, analyze or download. The PaVE provides scientists with the data and tools needed to accelerate scientific progress for the study and treatment of diseases caused by PVs.
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U2 - 10.1093/nar/gks984
DO - 10.1093/nar/gks984
M3 - Article
C2 - 23093593
AN - SCOPUS:84876540301
SN - 0305-1048
VL - 41
SP - D571-D578
JO - Nucleic acids research
JF - Nucleic acids research
IS - D1
ER -