THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Y. Z. Patt; S. Wallace; E. J. Freireich; V. P. Chuang; E. M. Hersh; G. M. Mavligit

doi:10.1016/S0140-6736(81)91671-8

THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Y. Z. Patt
, S. Wallace
, E. J. Freireich
, V. P. Chuang
, E. M. Hersh
, G. M. Mavligit

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Abstract

Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

Original language	English (US)
Pages (from-to)	349-351
Number of pages	3
Journal	The Lancet
Volume	317
Issue number	8216
DOIs	https://doi.org/10.1016/S0140-6736(81)91671-8
State	Published - Feb 14 1981
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER",

abstract = "Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4\% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).",

author = "Patt, \{Y. Z.\} and S. Wallace and Freireich, \{E. J.\} and Chuang, \{V. P.\} and Hersh, \{E. M.\} and Mavligit, \{G. M.\}",

year = "1981",

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doi = "10.1016/S0140-6736(81)91671-8",

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AU - Patt, Y. Z.

AU - Wallace, S.

AU - Freireich, E. J.

AU - Chuang, V. P.

AU - Hersh, E. M.

AU - Mavligit, G. M.

PY - 1981/2/14

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N2 - Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

AB - Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

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UR - https://www.scopus.com/pages/publications/0019350450#tab=citedBy

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DO - 10.1016/S0140-6736(81)91671-8

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JO - The Lancet

JF - The Lancet

IS - 8216

ER -

THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Abstract

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